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NAD(+)—diphthamide ADP-ribosyltransferase : ウィキペディア英語版 | NAD(+)—diphthamide ADP-ribosyltransferase
In enzymology, a NAD+-diphthamide ADP-ribosyltransferase () is an enzyme that catalyzes the chemical reaction :NAD+ + peptide diphthamide nicotinamide + peptide N-(ADP-D-ribosyl)diphthamide Thus, the two substrates of this enzyme are NAD+ and peptide diphthamide, whereas its two products are nicotinamide and peptide N-(ADP-D-ribosyl)diphthamide. This enzyme belongs to the family of glycosyltransferases, to be specific, the pentosyltransferases. The systematic name of this enzyme class is NAD+:peptide-diphthamide N-(ADP-D-ribosyl)transferase. Other names in common use include ADP-ribosyltransferase, mono(ADPribosyl)transferase, and NAD-diphthamide ADP-ribosyltransferase. ==Structural studies==
As of late 2007, 15 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , , , , , , , and .
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